Treatment of malignant pleural

Chinese medical Tribune (resident reporters Zhang Xianhuai) 50 years of Mr Wang caused pleural effusion large effusion of malignant pleural mesothelioma, chest tightness, dyspnea, in a number of hospital treatment. First affiliated hospital of Chinese PLA General Hospital Oncology epigenetic therapy for 4 weeks, Pleural effusions disappeared.　　　Recently in reviews, each target basically normal, pleural fluid control is good. Patient since June 2009 no incentive for chest and right pleural effusion, respiratory difficulties appear large effusion referring the institution. Director of Department of cancer for which xiaowenhua to conduct a comprehensive inspection, diagnosis of malignant pleural mesothelioma. Through a variety of chemotherapy in the treatment of thoracic cavity injection of cisplatin and bleomycin and many kinds of biological agents, inefficacy. Xiaowenhua the use of video-assisted Thoracoscopic epigenetic drugs injection and combined chemotherapy after 2 weeks, pleural fluid from blood into straw yellow liquid, effusion gradually decreased.　　　After 4 weeks, and pleural fluid of patients with chest tightness, breathing difficulties and other symptoms disappeared. Xiaowenhua said:   in recent years, foreign academics using the principles of epigenetic treatment of malignant tumors and achieved a remarkable effect. United States has approved the epigenetic drugs for bone marrow dysplasia syndromes, diseases such as leukemia, skin of t-lymphoid cells of clinical treatment.　　　Epigenetic drugs such as DNA methyltransferase inhibitors, or of histone acetyltransferase enzyme inhibitor, combined with chemotherapy for lung cancer was also achieved very good results. Xiaowenhua is China's first basic cancer epigenetics research and clinical treatment of one of the scholars. He uses – procaine, DNA methyltransferase inhibitors of histone acetyltransferase enzyme inhibitors – sodium valproate in treatment of refractory malignant pleural effusion in patients with 24 cases, achieved good results, as cancer therapy has opened up a new way.